MROCC Competency Statements, Topics on Examination and References

 

TOXICOLOGY, PHARMACOLOGY AND LAB ISSUES

Approximately 20% of the exam items are within this competency area

Competency Statement

The MRO must be knowledgeable of the toxicology & pharmacology of drugs of abuse.  While the MRO is not a laboratory director, the MRO must know what goes on in the laboratory and how quality is assured.  Knowledge in these areas will enable the MRO to:

  • recognize and describe the pharmaco/toxicokinetics of drugs of abuse and alcohol.

  • recognize both trade names and generic names for substances that are likely to appear in a drug screen, interfere with a drug test, or be presented to the MRO as a donor explanation for a positive drug test.

  • recognize the appropriate analytical methods for drug and alcohol screening and confirmation, and properly interpret results, with consideration of limits of detection, sensitivity, specificity, limitations, interferences, cost and availability.

  • advise clients regarding the use of various matrices and technologies for drug testing.

  • evaluate drug and alcohol testing services.

  • describe laboratory QA, QC, and certification requirements to an employer or other interested party.

  • efficiently transmit and receive drug test data and information while maintaining donor confidentiality.

  • evaluate laboratory findings relating to specimen validity.

  • recognize the basic types and mechanisms of action of performance enhancing drugs. 

Topics on Examination

  • Drugs of abuse

  • Alcohol

  • Analytical methods, new technologies

  • Laboratory quality control and COC

  • Laboratory certification

  • Laboratory communication with the MRO

  • Alcohol testing (analytical issues)

  • Specimen validity testing

References

  • Swotinsky RB, Smith DR, The Medical Review Officer's Manual.  Beverly Farms, MA, OEM Press, 4th ed. 2010, pages 95-130; 191-216.

  • Peterson KW, American College of Occupational and Environmental Medicine, Drug and Alcohol Testing Medical Review Officer Course Syllabus and Resource Manual, updated annually.  Sections on toxicology, pharmacology and laboratory issues.

  • American Society of Addiction Medicine, Medical Review Officer Course Manual, updated annually.  Sections on toxicology, pharmacology and laboratory issues.

  • Ropero-Miller JD, Goldberger BA, et al, Handbook of Workplace Drug Testing, AACC Press, 2nd ed. 2008.

  • Garriott JC (ed), Medicolegal Aspects of Alcohol, Lawyers & Judges Publishing Company, Inc., 5th edition, 2008.

GENERAL SUGGESTED REFERENCES & ON LINE RESOURCES