|
TOXICOLOGY, PHARMACOLOGY AND LAB ISSUES Approximately
20% of the exam items are within this competency area Competency Statement
The MRO must be
knowledgeable of the toxicology & pharmacology of
drugs of abuse. While the MRO is not a laboratory
director, the MRO must know what goes on in the
laboratory and how quality is assured. Knowledge
in these areas will enable the MRO to:
-
recognize and describe the
pharmaco/toxicokinetics of drugs of abuse and
alcohol.
-
recognize both trade names and
generic names for substances that are likely to
appear in a drug screen, interfere with a drug
test, or be presented to the MRO as a donor
explanation for a positive drug test.
-
recognize the appropriate
analytical methods for drug and alcohol
screening and confirmation, and properly
interpret results, with consideration of limits
of detection, sensitivity, specificity,
limitations, interferences, cost and
availability.
-
advise clients regarding the use
of various matrices and technologies for drug
testing.
-
evaluate drug and alcohol testing
services.
-
describe laboratory QA, QC, and
certification requirements to an employer or
other interested party.
-
efficiently transmit and receive
drug test data and information while maintaining
donor confidentiality.
-
evaluate laboratory findings
relating to specimen validity.
-
recognize the basic types and
mechanisms of action of performance enhancing
drugs.
Topics on Examination
-
Drugs of abuse
-
Alcohol
-
Analytical methods, new
technologies
-
Laboratory quality control and
COC
-
Laboratory certification
-
Laboratory communication with the
MRO
-
Alcohol testing (analytical
issues)
-
Specimen validity testing
References
-
Swotinsky RB, Smith DR, The
Medical Review Officer's Manual. Beverly
Farms, MA, OEM Press, 4th ed. 2010,
pages 95-130; 191-216.
-
Peterson KW, American College of
Occupational and Environmental Medicine, Drug
and Alcohol Testing Medical Review Officer
Course Syllabus and Resource Manual, updated
annually. Sections on toxicology, pharmacology
and laboratory issues.
-
American Society of Addiction
Medicine, Medical Review Officer Course
Manual, updated annually. Sections on
toxicology, pharmacology and laboratory issues.
-
Ropero-Miller JD, Goldberger BA,
et al, Handbook of Workplace Drug Testing,
AACC Press, 2nd ed. 2008.
-
Garriott JC (ed), Medicolegal
Aspects of Alcohol, Lawyers & Judges
Publishing Company, Inc., 5th
edition, 2008.
GENERAL SUGGESTED REFERENCES & ON LINE RESOURCES |